As we all are aware that germs on any surface can pass to you or another person. As the world introduced with new virus #corona, risk of infection increased. This deadly virus passed with air, touch. When we talk about the medical equipment disinfect, a dentist from a dental clinic in Noida tell that’ Medical equipment are physically present when other patients are having procedures done, and are at risk of having any number of pathogens accidentally getting on them in any number of ways. Thus the casual germ or some vicious pathogen can easily get onto the equipment. When the equipment is used again, these pathogens have a serious possibility of finding their way into the body of other patients. One patient’s illness can be transmitted to several other patients in this way. When the instruments or equipment is sterilized, this pathway for the spread of some pathogen is cut entirely’. So it is important to disinfect supplies and equipment. Disinfecting something means to clean it to destroy germs, it help prevent the spread of germs. There are many techniques disinfecting supplies and equipment. It start with rinsing after surgery, rinse instruments under warm running water then for cleaning the instruments submerged in a solution of water and detergent. After cleaning primary methods of medical sterilization occur from high temperature/pressure and chemical processes. 1. Cold sterilization. 2. Plasma gas sterilizers 3. Autoclaves 4. Vaporized hydrogen peroxide sterilizers 5. Heat 6. Ethylene oxide gas 7. Plasma, 8. Ozone 9. Radiation After any procedure the sterile surface/object is completely free of living microorganisms and viruses. It kills all microorganisms and prevents disease transmission associated with the use of that item. Classical sterilization techniques are best; it using saturated steam under pressure or hot air are the most reliable and should be used whenever possible.